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Recent discoveries indicate that the neural codes in the superficial layers of the primary visual cortex (V1) of macaque monkeys are complex, diverse, and super-sparse. This leads us to ponder the computational advantages and functional role of these “grandmother cells." Here, we propose that such cells can serve as prototype memory priors that bias and shape the distributed feature processing during the image generation process in the brain. These memory prototypes are learned by momentum online clustering and are utilized through a memory-based attention operation. Integrating this mechanism, we propose Memory Concept Attention (MoCA) to improve few-shot image generation quality. We show that having a prototype memory with attention mechanisms can improve image synthesis quality, learn interpretable visual concept clusters, and improve the robustness of the model. Our results demonstrate the feasibility of the idea that these super-sparse complex feature detectors can serve as prototype memory priors for modulating the image synthesis processes in the visual system